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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
8.18
Human Site:
S579
Identified Species:
18
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S579
N
G
R
L
V
V
G
S
F
S
R
R
K
K
K
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
P565
K
E
G
P
L
A
I
P
P
E
L
R
K
K
T
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S582
N
G
R
L
V
V
G
S
F
S
R
R
K
K
K
Dog
Lupus familis
XP_546733
1387
151432
G563
N
N
R
I
L
M
S
G
F
S
K
R
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S660
N
S
R
L
F
M
S
S
F
S
K
R
K
K
K
Rat
Rattus norvegicus
Q62688
1096
122754
V342
D
L
M
L
F
L
E
V
E
Q
G
V
T
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
G30
H
D
P
L
R
R
L
G
V
L
D
D
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
K554
Q
Q
I
R
Q
S
S
K
D
S
T
G
S
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
N654
Q
H
S
S
E
S
D
N
N
S
S
M
E
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
20
100
53.3
N.A.
66.6
6.6
N.A.
N.A.
0
0
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
80
N.A.
80
20
N.A.
N.A.
0
0
20
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
10
0
10
0
10
10
0
10
19
% D
% Glu:
0
10
0
0
10
0
10
0
10
10
0
0
19
0
0
% E
% Phe:
0
0
0
0
19
0
0
0
37
0
0
0
0
0
0
% F
% Gly:
0
19
10
0
0
0
19
19
0
0
10
10
0
0
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
10
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
19
0
46
46
37
% K
% Leu:
0
10
0
46
19
10
10
0
0
10
10
0
0
0
0
% L
% Met:
0
0
10
0
0
19
0
0
0
0
0
10
0
0
0
% M
% Asn:
37
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
19
10
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
37
10
10
10
0
0
0
0
19
46
0
0
0
% R
% Ser:
0
10
10
10
0
19
28
28
0
55
10
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% T
% Val:
0
0
0
0
19
19
0
10
10
0
0
10
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _